Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 5/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.32 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | LIG1 | P18858 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20177778 | 0.67 | KDM4E (0.36) | BRD4MEN1KMT2AGAAKDM1A | |
| SCHEMBL28939724 | 0.61 | BRD4 (0.43) | BRD4MDM2ALDH1A1CHRNA7TSHR | |
| SCHEMBL28939720 | 0.61 | BRD4 (0.43) | BRD4MDM2ALDH1A1CHRNA7TSHR | |
| SCHEMBL5612 | 0.60 | BRD4 (0.53) | BRD4MEN1KMT2ANPC1GAA | |
| SCHEMBL1673541 | 0.59 | LMNA (0.49) | BRD4CRBNMEN1KMT2ANPC1 | |
| SCHEMBL657720 | 0.59 | BRD4 (0.49) | BRD4MEN1KMT2ANPC1GAA | |
| SCHEMBL5647940 | 0.59 | BRD4 (0.44) | BRD4GAAKDM1AKCNH2MAOB | |
| SCHEMBL23119770 | 0.58 | BRD4 (0.47) | BRD4KDM1AKCNH2MAOBRCOR1 | |
| SCHEMBL20341692 | 0.58 | BRD4 (0.47) | BRD4MEN1KMT2ANPC1GAA | |
| SCHEMBL265495 | 0.58 | KDM1A (0.48) | BRD4KDM1AKCNH2MAOBRCOR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018092916-A1 | NITROGEN-CONTAINING POLYCYCLIC HETEROCYCLIC DERIVATIVE | 宇部興産株式会社 | 2018-05-24 | — | — | WO | disclosed |