Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 9/20 | 0.32 |
| ▸ | FPR1 | P21462 | 5/20 | 0.32 |
| ▸ | CPS1 | P31327 | 5/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20177908 | 0.86 | — | — | |
| SCHEMBL19559545 | 0.80 | FPR2 (0.33) | TAAR1KDM1AMAOAMAOBFPR2 | |
| SCHEMBL19559483 | 0.74 | FPR1 (0.40) | KDM1AMAOAMAOBFPR2FPR1 | |
| SCHEMBL20177609 | 0.73 | FPR2 (0.31) | TAAR1FPR2 | |
| SCHEMBL20041817 | 0.70 | GCK (0.35) | FPR2FPR1 | |
| SCHEMBL18117745 | 0.70 | GCK (0.35) | FPR2FPR1 | |
| SCHEMBL16785337 | 0.67 | PDE4A (0.49) | FPR2FPR1 | |
| SCHEMBL20177630 | 0.67 | FPR1 (0.38) | TAAR1FPR2FPR1 | |
| SCHEMBL19559455 | 0.67 | PDE4A (0.49) | FPR2FPR1 | |
| SCHEMBL19559459 | 0.66 | PDE4A (0.50) | FPR1CPS1ALDH1A1HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018092916-A1 | NITROGEN-CONTAINING POLYCYCLIC HETEROCYCLIC DERIVATIVE | 宇部興産株式会社 | 2018-05-24 | — | — | WO | disclosed |