Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 6/20 | 0.35 |
| ▸ | IGF1R | P08069 | 3/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | HPGDS | O60760 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.32 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | FPR1 | P21462 | 2/20 | 0.30 |
| ▸ | FPR2 | P25090 | 2/20 | 0.30 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18117745 | 1.00 | GCK (0.35) | GCKIGF1RTYK2CSNK2A1HPGDS | |
| SCHEMBL19559570 | 0.93 | GCK (0.34) | GCKIGF1RTYK2CSNK2A1HPGDS | |
| SCHEMBL19559483 | 0.79 | FPR1 (0.40) | MEN1NPC1TP53RAB9AKMT2A | |
| SCHEMBL19559545 | 0.78 | FPR2 (0.33) | FPR1FPR2 | |
| SCHEMBL20177609 | 0.71 | FPR2 (0.31) | FPR2 | |
| SCHEMBL20177582 | 0.70 | TAAR1 (0.39) | FPR1FPR2 | |
| SCHEMBL18106702 | 0.67 | FPR2 (0.60) | FPR1FPR2 | |
| SCHEMBL19547807 | 0.67 | FPR2 (0.60) | FPR1FPR2 | |
| SCHEMBL29434436 | 0.67 | FPR2 (0.60) | FPR1FPR2 | |
| SCHEMBL9820163 | 0.64 | ABCB11 (0.61) | IGF1RCSNK2A1MEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3305763-A1 | DEUTERATED OR ISOTOPICALLY LABELED UREA DERIVATIVES OR PHARMACOLOGICALLY ACCEPTABLE SALTS THEREOF USEFUL AS FPRL-1 AGONISTS | Kyorin Pharmaceutical Co., Ltd. (JP) | 2018-04-11 | — | — | EP | disclosed |