SCHEMBL2017760

SCHEMBL2017760

NCc1cnc2ccccn12

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GGPS1 O95749 1/20 0.53
FDPS P14324 1/20 0.53
GPR84 Q9NQS5 1/20 0.49
DRD4 P21917 1/20 0.47
DRD3 P35462 1/20 0.47
NPSR1 Q6W5P4 2/20 0.46
FLT3 P36888 1/20 0.45
PKM P14618 1/20 0.44
TGFBR1 P36897 1/20 0.44
ADORA3 P0DMS8 1/20 0.43
IRAK4 Q9NWZ3 1/20 0.43
MIF P14174 1/20 0.41
PRMT5 O14744 1/20 0.41
WDR77 Q9BQA1 1/20 0.41
KDM4E B2RXH2 2/20 0.41
ALDH1A1 P00352 2/20 0.41
NPC1 O15118 2/20 0.41
GLA P06280 1/20 0.41
GAA P10253 1/20 0.41
HPGD P15428 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL29899404 0.98 GGPS1 (0.51) GGPS1FDPSGPR84DRD4DRD3
SCHEMBL3796430 0.85 GGPS1 (0.50) GGPS1FDPSGPR84DRD4DRD3
SCHEMBL9797098 0.81 GGPS1 (0.56) GGPS1FDPSGPR84DRD4DRD3
SCHEMBL28036377 0.81 GGPS1 (0.53) GGPS1FDPSGPR84DRD4DRD3
SCHEMBL5755912 0.81 GGPS1 (0.53) GGPS1FDPSGPR84DRD4DRD3
SCHEMBL8360107 0.81 GGPS1 (0.53) GGPS1FDPSGPR84DRD4DRD3
SCHEMBL25767061 0.81 GGPS1 (0.53) GGPS1FDPSGPR84DRD4DRD3
SCHEMBL18265799 0.81 GGPS1 (0.53) GGPS1FDPSGPR84DRD4DRD3
Hydrochloric Acid SCHEMBL2180991 0.79 GGPS1 (0.51) GGPS1FDPSGPR84DRD4DRD3
Hydrochloric Acid SCHEMBL5655467 0.79 GGPS1 (0.55) GGPS1FDPSGPR84DRD4DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116769295-B Conductive PC (polycarbonate) for conductive carrier tape sheet and preparation method thereof 浦江亿通塑胶电子有限公司 2024-02-23 CN claimed
CN-116769295-A Conductive PC (polycarbonate) for conductive carrier tape sheet and preparation method thereof 浦江亿通塑胶电子有限公司 2023-09-19 CN claimed
CN-115369430-A Synthetic method of 3-aminomethyl imidazo [1,2-a ] pyridine derivative 深圳职业技术学院 2022-11-22 CN claimed
WO-2011073269-A1 PIPERIDINE ARYL SULFONAMIDE DERIVATIVES AS KV1.3 MODULATORS EVOTEC AG (DE) 2011-06-23 WO claimed
US-7342025-B2 Substituted C-imidazo[1,2-a]pyridin-3-yl-methylamines GRUENENTHAL GMBH (DE) 2008-03-11 US claimed
EP-1549647-B1 SUBSTITUTED C-IMIDAZO¬1,2-A|PYRIDIN-3-YL-METHYLAMINES GRUENENTHAL GMBH (DE) 2006-04-12 EP claimed
EP-1549650-B1 SUBSTITUTED C-IMIDAZO[1,2-A]PYRIDIN-3-YL-METHYLAMINES GRUENENTHAL GMBH (DE) 2006-03-22 EP claimed
US-20050239822-A1 Substituted C-imiadazol[1,2-a] pyridin-3-yl-methylamines GRUENENTHAL GMBH (DE) 2005-10-27 US claimed
EP-1549650-A1 SUBSTITUTED C-IMIDAZO[1,2-A]PYRIDIN-3-YL-METHYLAMINES Grünenthal GmbH (DE) 2005-07-06 EP claimed
EP-1549647-A1 SUBSTITUTED C-IMIDAZO[1,2-A]PYRIDIN-3-YL-METHYLAMINES Grünenthal GmbH (DE) 2005-07-06 EP claimed
WO-2004035578-A1 SUBSTITUTED C-IMIDAZO[1,2-A]PYRIDIN-3-YL-METHYLAMINES Grünenthal GmbH (DE) 2004-04-29 WO claimed
WO-2004033453-A1 SUBSTITUTED C-IMIDAZO[1,2-A]PYRIDIN-3-YL-METHYLAMINES Grünenthal GmbH (DE) 2004-04-22 WO claimed
US-12358910-B2 Heteroaromatic compounds as Vanin inhibitors BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2025-07-15 US disclosed
CN-113166117-B Heteroaromatic compounds as VANIN inhibitors 勃林格殷格翰国际公司 2025-04-15 CN disclosed
EP-3487856-B1 SUBSTITUTED DIAZAHETERO-BICYCLIC COMPOUNDS AND THEIR USE BAYER AG (DE) 2025-01-22 EP disclosed
CN-116769295-B Conductive PC (polycarbonate) for conductive carrier tape sheet and preparation method thereof 浦江亿通塑胶电子有限公司 2024-02-23 CN disclosed
WO-2004033453-A1 SUBSTITUTED C-IMIDAZO[1,2-A]PYRIDIN-3-YL-METHYLAMINES Grünenthal GmbH (DE) 2004-04-22 WO disclosed
WO-2002066478-A1 ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE ASTRAZENECA AB (SE) 2002-08-29 WO disclosed
US-5441945-A Bone resorption inhibitor, anticaries agent, polyvalent metal ion complex salt forming agent HOECHST JAPAN LIMITED (JP) 1995-08-15 US disclosed
EP-0620227-A1 Heterocyclic iminobismethylenebisphosphonic acid derivatives HOECHST JAPAN LIMITED (JP) 1994-10-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050239822-A1 Substituted C-imiadazol[1,2-a] pyridin-3-yl-methylamines NOS2, NOS1, NOS3 GGPS1 899/4885FDPS 407/4885GPR84 3808/4885
US-12358910-B2 Heteroaromatic compounds as Vanin inhibitors VHL, FANCI, PAH GGPS1 935/4885FDPS 124/4885GPR84 2609/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.