Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.47 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.47 |
| ▸ | F2RL1 | P55085 | 5/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | FPR2 | P25090 | 4/20 | 0.40 |
| ▸ | FPR1 | P21462 | 3/20 | 0.40 |
| ▸ | EDNRB | P24530 | 1/20 | 0.38 |
| ▸ | EDNRA | P25101 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | QPCT | Q16769 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20177873 | 0.85 | FPR2 (0.44) | KDM1AKDM1BF2RL1HTR2AHRH1 | |
| SCHEMBL20177703 | 0.84 | FPR2 (0.56) | HTR2AFPR2FPR1 | |
| SCHEMBL20177819 | 0.82 | FPR2 (0.45) | F2RL1HTR2AHRH1FPR2FPR1 | |
| SCHEMBL16785453 | 0.81 | FPR2 (0.58) | FPR2FPR1 | |
| SCHEMBL29434429 | 0.81 | FPR2 (0.58) | FPR2FPR1 | |
| SCHEMBL18579681 | 0.81 | FPR2 (0.58) | FPR2FPR1 | |
| SCHEMBL19996023 | 0.79 | FPR2 (0.37) | F2RL1HTR2AHRH1FPR2FPR1 | |
| SCHEMBL20177486 | 0.77 | F2RL1 (0.54) | KDM1AKDM1BF2RL1HTR2AHRH1 | |
| SCHEMBL20177580 | 0.77 | KDM1A (0.45) | KDM1AKDM1BFPR2FPR1 | |
| SCHEMBL16785361 | 0.76 | LMNA (0.36) | F2RL1FPR2FPR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018092916-A1 | NITROGEN-CONTAINING POLYCYCLIC HETEROCYCLIC DERIVATIVE | 宇部興産株式会社 | 2018-05-24 | — | — | WO | disclosed |