SCHEMBL20178548

SCHEMBL20178548

CC[Si](CC)(CC)c1ccc([C]=O)cc1

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 2/20 0.41
NR1H3 Q13133 2/20 0.41
ESR1 P03372 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10490647 0.85 NR1H2 (0.47) NR1H2NR1H3ESR1
SCHEMBL10490632 0.82 NR1H2 (0.44) NR1H2NR1H3ESR1
SCHEMBL2170875 0.80 NR1H2 (0.43) NR1H2NR1H3ESR1
SCHEMBL7056361 0.79 NR1H2 (0.54) NR1H2NR1H3ESR1
SCHEMBL10490688 0.76
SCHEMBL7637235 0.76
SCHEMBL7632023 0.76
SCHEMBL7630021 0.75 NR1H2 (0.37) NR1H2NR1H3
SCHEMBL7203053 0.73 ALDH1A1 (0.39) NR1H2NR1H3ESR1
SCHEMBL104811 0.72 APP (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113166519-A Blends of cyclic olefin copolymers and films made therefrom 埃克森美孚化学专利公司 2021-07-23 CN disclosed
CN-108884186-B Comb-block high density polyethylene and method for making same 埃克森美孚化学专利公司 2020-12-25 CN disclosed
US-9982081-B2 Cyclic olefin copolymers and methods of making them EXXONMOBIL CHEMICAL PATENTS INC. (US) 2018-05-29 US disclosed