SCHEMBL2170875

SCHEMBL2170875

CC[Si](CC)(CC)c1ccc([C]c2ccc([Si](CC)(CC)CC)cc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 2/20 0.43
NR1H3 Q13133 2/20 0.43
ESR1 P03372 2/20 0.36
CYP2A6 P11509 1/20 0.31
AR P10275 1/20 0.30
ESR2 Q92731 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7203053 0.91 ALDH1A1 (0.39) NR1H2NR1H3ESR1CYP2A6AR
SCHEMBL7056361 0.83 NR1H2 (0.54) NR1H2NR1H3ESR1ARESR2
SCHEMBL6250873 0.82 HSD17B10 (0.44) ESR1
SCHEMBL20178548 0.80 NR1H2 (0.41) NR1H2NR1H3ESR1
SCHEMBL988371 0.72 ACHE (0.47) NR1H2NR1H3ESR1CYP2A6AR
SCHEMBL6226134 0.72 NR1H2 (0.39) NR1H2NR1H3
SCHEMBL23190380 0.70 NR1H2 (0.50) NR1H2NR1H3ESR1
SCHEMBL16537645 0.70 ESR1 (0.68) NR1H2NR1H3ESR1ARESR2
SCHEMBL2168523 0.70 NR1H2 (0.45) NR1H2NR1H3ESR1ARESR2
SCHEMBL9243328 0.70 NR1H2 (0.45) NR1H2NR1H3ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 171 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230242745-A1 Process for Production of Thermoplastic Vulcanizates using Supported Catalyst Systems and Compositions Made Therefrom EXXONMOBIL CHEMICAL PATENTS INC (US) 2023-08-03 US claimed
WO-2023081325-A1 SYNDIOTACTIC PROPYLENE-BASED ETHYLENE-PROPYLENE COPOLYMERS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2023-05-11 WO claimed
US-20230148328-A1 SYNDIOTACTIC PROPYLENE-BASED ETHYLENE- PROPYLENE COPOLYMERS EXXONMOBIL CHEMICAL PATENTS INC (US) 2023-05-11 US claimed
US-20190144653-A1 Bimodal Ethylene, Alpha-Olefin, and Diene Polymers Using Dual Organometallic Catalysts EXXONMOBIL CHEMICAL PATENTS INC. 2019-05-16 US claimed
US-9422385-B2 Polyethylene copolymers with vinyl terminated macromonomers as comonomers EXXONMOBIL CHEMICAL PATENTS INC. (US) 2016-08-23 US claimed
EP-2528957-B1 COPOLYMERS, COMPOSITIONS THEREOF, AND METHODS FOR MAKING THEM EXXONMOBIL CHEM PATENTS INC (US) 2014-10-22 EP claimed
US-8618219-B2 Propylene copolymers for adhesive applications EXXONMOBIL CHEMICAL PATENTS INC. (US) 2013-12-31 US claimed
US-8378048-B2 Copolymers, compositions thereof, and methods for making them EXXONMOBIL CHEMICAL PATENTS INC. (US) 2013-02-19 US claimed
EP-2528957-A1 COPOLYMERS, COMPOSITIONS THEREOF, AND METHODS FOR MAKING THEM ExxonMobil Chemical Patents Inc. (US) 2012-12-05 EP claimed
EP-1196464-B9 BRIDGED METALLOCENES FOR OLEFIN COPOLYMERIZATION EXXONMOBIL CHEM PATENTS INC (US) 2005-03-23 EP claimed
EP-1196464-B1 BRIDGED METALLOCENES FOR OLEFIN COPOLYMERIZATION EXXON CHEMICAL PATENTS INC (US) 2004-12-08 EP claimed
US-6528670-B1 Such as di(p-trimethylsilyl-phenyl)methylene(cyclopenta-dienyl)(fluorenyl) hafnium dimethyl; solution polymerization catalysts EXXONMOBIL CHEMICAL PATENTS INC. 2003-03-04 US claimed
US-6506857-B2 Di(p-trimethylsilyl-phenyl) methylene (cyclopentadienyl) (fluorenyl) hafnium dimethyl, for example; ethylene solution polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2003-01-14 US claimed
US-20020137959-A1 Bridged metallocenes for olefin copolymerization RIX FRANCIS C (US) 2002-09-26 US claimed
EP-1196464-A1 BRIDGED METALLOCENES FOR OLEFIN COPOLYMERIZATION Exxon Chemical Patents, Inc. (US) 2002-04-17 EP claimed
WO-2000024793-A1 BRIDGED METALLOCENES FOR OLEFIN COPOLYMERIZATION EXXON CHEMICAL PATENTS INC. (US) 2000-05-04 WO claimed
EP-3341437-B1 ETHYLENE COPOLYMER WITH IN-SITU OIL PRODUCTION EXXONMOBIL CHEMICAL PATENTS INC (US) 2024-04-10 EP disclosed
WO-2024073260-A1 ETHYLENE COPOLYMERS FOR PHOTOVOLTAIC CELLS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2024-04-04 WO disclosed
WO-2002000666-A1 SILOXY SUBSTITUTED COCATALYST ACTIVATORS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2002-01-03 WO disclosed
WO-2000024793-A1 BRIDGED METALLOCENES FOR OLEFIN COPOLYMERIZATION EXXON CHEMICAL PATENTS INC. (US) 2000-05-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020137959-A1 Bridged metallocenes for olefin copolymerization ERBB4, ERBB3, ERBB2 NR1H2 3201/4885NR1H3 2540/4885ESR1 29/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.