Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 1/20 | 0.42 |
| ▸ | ARG2 | P78540 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 3/20 | 0.38 |
| ▸ | NOS1 | P29475 | 2/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 4/20 | 0.35 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.34 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.33 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16447139 | 1.00 | ARG1 (0.42) | ARG1ARG2NOS2NOS1NOS3 | |
| SCHEMBL17852295 | 1.00 | ARG1 (0.42) | ARG1ARG2NOS2NOS1NOS3 | |
| SCHEMBL1700570 | 0.86 | ARG1 (0.37) | ARG1ARG2NOS2NOS1NOS3 | |
| SCHEMBL1700571 | 0.86 | ARG1 (0.37) | ARG1ARG2NOS2NOS1NOS3 | |
| SCHEMBL24185361 | 0.81 | DDAH1 (0.46) | DDAH1CASP1SLC1A3SLC1A1GRIK1 | |
| SCHEMBL20192745 | 0.80 | ARG1 (0.44) | ARG1ARG2NOS2NOS1NOS3 | |
| SCHEMBL28297586 | 0.78 | DDAH1 (0.57) | ARG1ARG2NOS2DDAH1CASP1 | |
| SCHEMBL22281180 | 0.78 | DDAH1 (0.57) | ARG1ARG2NOS2DDAH1CASP1 | |
| SCHEMBL7194971 | 0.78 | DDAH1 (0.57) | ARG1ARG2NOS2DDAH1CASP1 | |
| SCHEMBL17852438 | 0.78 | ARG1 (0.42) | ARG1ARG2NOS2NOS1NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9981908-B2 | Amino acid derivatives | MEDIMMUNE LIMITED (GB) | 2018-05-29 | — | — | US | disclosed |