Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 15/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20179122 | 1.00 | FOLH1 (0.50) | FOLH1LMNAGAASLC7A5 | |
| SCHEMBL21577906 | 0.94 | LMNA (0.50) | FOLH1LMNAGAA | |
| SCHEMBL20179218 | 0.94 | LMNA (0.50) | FOLH1LMNAGAA | |
| SCHEMBL20179268 | 0.94 | LMNA (0.50) | FOLH1LMNAGAA | |
| SCHEMBL20168691 | 0.90 | FOLH1 (0.47) | FOLH1LMNAGAASLC7A5 | |
| SCHEMBL21578047 | 0.89 | LMNA (0.44) | FOLH1LMNAGAASLC7A5 | |
| SCHEMBL20168729 | 0.89 | FOLH1 (0.62) | FOLH1LMNA | |
| SCHEMBL26039166 | 0.87 | LMNA (0.42) | FOLH1LMNAGAASLC7A5 | |
| SCHEMBL21570571 | 0.85 | LMNA (0.46) | FOLH1LMNAGAASLC7A5 | |
| SCHEMBL21578062 | 0.84 | LMNA (0.51) | LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018094334-A1 | PRODRUGS OF HYDROXAMATE-BASED GCPII INHIBITORS | THE JOHNS HOPKINS UNIVERSITY (US) | 2018-05-24 | — | — | WO | disclosed |