Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 6/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.38 |
| ▸ | RELA | Q04206 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | MEP1B | Q16820 | 3/20 | 0.38 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MEP1A | Q16819 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24023448 | 0.95 | LMNA (0.48) | LMNAGAA | |
| SCHEMBL21578047 | 0.88 | LMNA (0.44) | LMNAGAAMRGPRX4FOLH1PKM | |
| SCHEMBL20179122 | 0.87 | FOLH1 (0.50) | LMNAGAAFOLH1SLC7A5 | |
| SCHEMBL20179245 | 0.87 | FOLH1 (0.50) | LMNAGAAFOLH1SLC7A5 | |
| SCHEMBL26038893 | 0.83 | FOLH1 (0.44) | FOLH1MEP1BSLC7A5ANPEPENPEP | |
| SCHEMBL20168691 | 0.83 | FOLH1 (0.47) | LMNAGAAMRGPRX4FOLH1PKM | |
| SCHEMBL21578062 | 0.83 | LMNA (0.51) | LMNAGAAMRGPRX4 | |
| SCHEMBL21577906 | 0.82 | LMNA (0.50) | LMNAGAAFOLH1 | |
| SCHEMBL20179268 | 0.82 | LMNA (0.50) | LMNAGAAFOLH1 | |
| SCHEMBL20179218 | 0.82 | LMNA (0.50) | LMNAGAAFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023154939-A2 | GCPII INHIBITION FOR THE TREATMENT OF SARCOPENIA AND AGING | THE JOHNS HOPKINS UNIVERSITY (US) | 2023-08-17 | — | — | WO | disclosed |