Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18649662 | 1.00 | SIGMAR1 (0.34) | SIGMAR1 | |
| SCHEMBL23340924 | 0.84 | TSHR (0.36) | — | |
| SCHEMBL20751513 | 0.82 | ALDH1A1 (0.42) | SIGMAR1 | |
| SCHEMBL16864248 | 0.81 | KMT2A (0.33) | SIGMAR1 | |
| SCHEMBL19846896 | 0.81 | SIGMAR1 (0.33) | SIGMAR1 | |
| SCHEMBL21162472 | 0.79 | CYP2D6 (0.31) | — | |
| SCHEMBL11506624 | 0.79 | SIGMAR1 (0.32) | SIGMAR1 | |
| SCHEMBL7960833 | 0.79 | LMNA (0.37) | — | |
| SCHEMBL21799610 | 0.79 | MEN1 (0.30) | — | |
| SCHEMBL10496398 | 0.79 | LMNA (0.37) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018093695-A1 | FACTOR XIIa INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2018-05-24 | — | — | WO | disclosed |