Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 4/20 | 0.39 |
| ▸ | NOS1 | P29475 | 4/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17525497 | 0.89 | NOS3 (0.42) | NOS3NOS1HTR1ASLC6A4NOS2 | |
| SCHEMBL17525496 | 0.88 | NOS3 (0.43) | NOS3NOS1HTR1ASLC6A4NOS2 | |
| SCHEMBL17525495 | 0.87 | NOS1 (0.41) | NOS3NOS1HTR1ASLC6A4NOS2 | |
| SCHEMBL17525489 | 0.86 | NOS3 (0.43) | NOS3NOS1HTR1ASLC6A4NOS2 | |
| SCHEMBL17525478 | 0.86 | NOS3 (0.43) | NOS3NOS1HTR1ASLC6A4NOS2 | |
| SCHEMBL17525491 | 0.85 | KDM1A (0.45) | NOS3NOS1HTR1ASLC6A4NOS2 | |
| SCHEMBL17859565 | 0.85 | NOS3 (0.40) | NOS3NOS1HTR1ASLC6A4NOS2 | |
| SCHEMBL17525488 | 0.84 | NOS3 (0.44) | NOS3NOS1HTR1ASLC6A4NOS2 | |
| SCHEMBL17525490 | 0.83 | KDM1A (0.43) | NOS3NOS1NOS2CYP2D6KDM1A | |
| SCHEMBL17525487 | 0.82 | NOS3 (0.46) | NOS3NOS1HTR1ASLC6A4NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180141922-A1 | BENZOXAZINE DERIVATIVES AND USE IN HAIR DYEING | L'OREAL (FR) | 2018-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180141922-A1 | BENZOXAZINE DERIVATIVES AND USE IN HAIR DYEING | XDH, KRT18, CYC1 | NOS3 602/4885NOS1 1127/4885HTR1A 802/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.