Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.55 |
| ▸ | ACACB | O00763 | 3/20 | 0.54 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.46 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CCR5 | P51681 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20165040 | 0.86 | ESR1 (0.48) | MCHR1ACACBKDM4EALDH1A1LMNA | |
| SCHEMBL20179666 | 0.86 | ESR1 (0.48) | MCHR1ACACBKDM4EALDH1A1LMNA | |
| SCHEMBL20165043 | 0.86 | ESR1 (0.48) | MCHR1ACACBKDM4EALDH1A1LMNA | |
| SCHEMBL20179695 | 0.82 | MCHR1 (0.58) | MCHR1ACACBCHRNB2CHRNA5CHRNA7 | |
| SCHEMBL13772738 | 0.79 | NR4A1 (0.62) | MAOBALDH1A1LMNAEGFRNR4A1 | |
| SCHEMBL6210392 | 0.79 | RAB9A (0.58) | MAOBALDH1A1NR4A1NR4A2NR4A3 | |
| SCHEMBL6208904 | 0.79 | RAB9A (0.58) | MAOBALDH1A1NR4A1NR4A2NR4A3 | |
| SCHEMBL3270043 | 0.74 | NR4A1 (0.55) | MAOBALDH1A1LMNAEGFRNR4A1 | |
| SCHEMBL26815710 | 0.73 | RXRB (0.53) | SLC6A5MAOBNR4A1NR4A2NR4A3 | |
| SCHEMBL14487845 | 0.72 | CHRNB2 (0.54) | CHRNB2CHRNA5CHRNA7CHRNA4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018091153-A1 | NOVEL SUBSTITUTED N-(3-FLUOROPROPYL)-PYRROLIDINE COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND THERAPEUTIC USES THEREOF | SANOFI (FR) | 2018-05-24 | — | — | WO | disclosed |