Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.58 |
| ▸ | EGFR | P00533 | 6/20 | 0.51 |
| ▸ | ACACB | O00763 | 2/20 | 0.51 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.48 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.48 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.48 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | CCR5 | P51681 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | HRH2 | P25021 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20165409 | 0.85 | ESR1 (0.50) | EGFRCCR5ALDH1A1HRH2HRH1 | |
| SCHEMBL20165412 | 0.85 | ESR1 (0.50) | EGFRCCR5ALDH1A1HRH2HRH1 | |
| SCHEMBL20179696 | 0.82 | MCHR1 (0.55) | MCHR1EGFRACACBSLC6A5CHRNB2 | |
| SCHEMBL4220632 | 0.79 | NR4A1 (0.72) | EGFRL3MBTL1ALDH1A1GAAMAPT | |
| SCHEMBL26815710 | 0.78 | RXRB (0.53) | SLC6A5RAB9ASMN1; SMN2MAOB | |
| SCHEMBL1419819 | 0.76 | L3MBTL1 (0.70) | EGFRL3MBTL1ALDH1A1GAAMAPT | |
| SCHEMBL6208174 | 0.76 | L3MBTL1 (0.70) | EGFRL3MBTL1ALDH1A1GAAMAPT | |
| SCHEMBL14487845 | 0.75 | CHRNB2 (0.54) | CHRNB2CHRNA5CHRNA7CHRNA4ALDH1A1 | |
| SCHEMBL17869370 | 0.75 | ALDH1A1 (0.55) | ACACBALDH1A1SMN1; SMN2 | |
| SCHEMBL22664149 | 0.75 | ALDH1A1 (0.55) | ACACBALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018091153-A1 | NOVEL SUBSTITUTED N-(3-FLUOROPROPYL)-PYRROLIDINE COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND THERAPEUTIC USES THEREOF | SANOFI (FR) | 2018-05-24 | — | — | WO | disclosed |