Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 11/20 | 0.63 |
| ▸ | MTNR1B | P49286 | 11/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20544602 | 0.94 | MTNR1A (0.60) | MTNR1AMTNR1BALDH1A1LMNATHRB | |
| SCHEMBL23226196 | 0.91 | MTNR1A (0.66) | MTNR1AMTNR1BALDH1A1LMNATHRB | |
| SCHEMBL3169884 | 0.88 | MTNR1B (0.55) | MTNR1AMTNR1BALDH1A1LMNATHRB | |
| SCHEMBL4405658 | 0.87 | ALDH1A1 (0.61) | MTNR1AMTNR1BALDH1A1LMNATHRB | |
| SCHEMBL20165074 | 0.86 | ALDH1A1 (0.59) | MTNR1AMTNR1BALDH1A1LMNATHRB | |
| SCHEMBL29756921 | 0.84 | MTNR1A (0.58) | MTNR1AMTNR1BALDH1A1LMNATHRB | |
| SCHEMBL12470557 | 0.82 | ALDH1A1 (0.62) | MTNR1AMTNR1BALDH1A1LMNATHRB | |
| SCHEMBL4272836 | 0.82 | MTNR1A (0.58) | MTNR1AMTNR1BALDH1A1LMNATHRB | |
| SCHEMBL4271362 | 0.82 | MTNR1A (0.58) | MTNR1AMTNR1BALDH1A1LMNATHRB | |
| SCHEMBL4267817 | 0.82 | MTNR1A (0.58) | MTNR1AMTNR1BALDH1A1LMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018091153-A1 | NOVEL SUBSTITUTED N-(3-FLUOROPROPYL)-PYRROLIDINE COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND THERAPEUTIC USES THEREOF | SANOFI (FR) | 2018-05-24 | — | — | WO | disclosed |