Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.38 |
| ▸ | PPARA | Q07869 | 3/20 | 0.38 |
| ▸ | PPARD | Q03181 | 2/20 | 0.38 |
| ▸ | CETP | P11597 | 4/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | TACR1 | P25103 | 2/20 | 0.31 |
| ▸ | PTGES | O14684 | 2/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20137060 | 0.87 | MGLL (0.41) | PPARGPPARAPPARDCETPNR1H2 | |
| SCHEMBL20137125 | 0.86 | MGLL (0.39) | PPARGPPARAPPARDCETPNR1H2 | |
| SCHEMBL20157947 | 0.81 | PPARG (0.36) | PPARGPPARAPPARDCETPNR1H2 | |
| SCHEMBL20137037 | 0.80 | KDM4E (0.38) | PPARGPPARAPPARDCETPNR1H2 | |
| SCHEMBL20166910 | 0.80 | KDM4E (0.39) | PPARGPPARAPPARDCETPNR1H2 | |
| Hydrochloric Acid SCHEMBL20137043 | 0.80 | KDM4E (0.37) | PPARGPPARAPPARDCETPNR1H2 | |
| SCHEMBL20166820 | 0.79 | ALOX5 (0.40) | PPARGPPARAPPARDCETPNR1H2 | |
| SCHEMBL20137089 | 0.79 | FFAR4 (0.39) | PPARGPPARAPPARDCETPNR1H2 | |
| SCHEMBL29561187 | 0.79 | FFAR4 (0.39) | PPARGPPARAPPARDCETPNR1H2 | |
| Hydrochloric Acid SCHEMBL20137048 | 0.78 | FFAR4 (0.39) | PPARGPPARAPPARDCETPNR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018093947-A1 | MAGL INHIBITORS | ABIDE THERAPEUTICS, INC. (US) | 2018-05-24 | — | — | WO | disclosed |