Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3579067 | 0.93 | OPRD1 (0.48) | OPRD1 | |
| SCHEMBL13441354 | 0.93 | OPRD1 (0.48) | OPRD1 | |
| SCHEMBL3579068 | 0.93 | OPRD1 (0.48) | OPRD1 | |
| SCHEMBL15456976 | 0.87 | OPRD1 (0.56) | OPRD1OPRM1 | |
| SCHEMBL3574392 | 0.87 | OPRD1 (0.52) | OPRD1 | |
| SCHEMBL3574395 | 0.87 | OPRD1 (0.52) | OPRD1 | |
| SCHEMBL13441329 | 0.87 | OPRD1 (0.52) | OPRD1 | |
| SCHEMBL15450316 | 0.87 | OPRD1 (0.53) | OPRD1OPRM1 | |
| SCHEMBL3576994 | 0.85 | CYP1A2 (0.51) | OPRD1OPRM1 | |
| SCHEMBL13441355 | 0.85 | CYP1A2 (0.51) | OPRD1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10730851-B2 | Polymorph of triaryldimethylpiperazine dihydrochloride and preparation method and application thereof | YUNNAN INSTITUTE OF MATERIA MEDICA (CN) | 2020-08-04 | — | — | US | disclosed |
| US-20190270720-A1 | POLYMORPH OF TRIARYLDIMETHYLPIPERAZINE DIHYDROCHLORIDE AND PREPARATION METHOD AND APPLICATION THEREOF | YUNNAN INSTITUTE OF MATERIA MEDICA (CN) | 2019-09-05 | — | — | US | disclosed |
| WO-2018090360-A1 | POLYMORPH OF TRIARYLDIMETHYLPIPERAZINE DIHYDROCHLORIDE AND PREPARATION METHOD AND APPLICATION THEREOF | 云南省药物研究所 | 2018-05-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190270720-A1 | POLYMORPH OF TRIARYLDIMETHYLPIPERAZINE DIHYDROCHLORIDE AND PREPARATION METHOD AND APPLICATION THEREOF | OPRK1, OPRM1, OPRD1 | OPRD1 3/4885OPRM1 2/4885 |
| US-10730851-B2 | Polymorph of triaryldimethylpiperazine dihydrochloride and preparation method and application thereof | OPRK1, OPRM1, OPRD1 | OPRD1 3/4885OPRM1 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.