Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 8/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | EYA3 | Q99504 | 3/20 | 0.36 |
| ▸ | TTR | P02766 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | EYA2 | O00167 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.36 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20181584 | 0.81 | MAPK1 (0.48) | MAPK1ALOX15HPGDKDM4ELMNA | |
| SCHEMBL20181576 | 0.78 | SLC22A12 (0.38) | MAPK1SLC22A12HPGDKDM4EEYA3 | |
| SCHEMBL18629839 | 0.77 | MAPK1 (0.46) | MAPK1SLC22A12HPGDKDM4ETDP1 | |
| SCHEMBL20181579 | 0.76 | SLC22A12 (0.37) | MAPK1SLC22A12HPGDEYA3TTR | |
| SCHEMBL20181615 | 0.76 | ALDH1A1 (0.47) | MAPK1SLC22A12HPGDKDM4EEYA3 | |
| SCHEMBL18629885 | 0.76 | SLC22A12 (0.38) | MAPK1SLC22A12HPGDEYA3TTR | |
| SCHEMBL20181585 | 0.76 | MAPK1 (0.48) | MAPK1ALOX15HPGDKDM4EALDH1A1 | |
| SCHEMBL20181390 | 0.76 | SLC22A12 (0.39) | MAPK1SLC22A12HPGDKDM4EEYA3 | |
| SCHEMBL18629847 | 0.76 | SLC22A12 (0.43) | MAPK1SLC22A12HPGDEYA3TTR | |
| SCHEMBL18629835 | 0.75 | RAB9A (0.44) | MAPK1SLC22A12HPGDKDM4EEYA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE50083-E1 | URAT1 inhibitor and use thereof | JIANGSU ATOM BIOSCIENCE AND PHARMACEUTICAL CO., LTD. (CN) | 2024-08-20 | — | — | US | disclosed |
| EP-3543240-B1 | URAT1 INHIBITOR AND USE THEREOF | JIANGSU ATOM BIOSCIENCE AND PHARMACEUTICAL CO LTD (CN) | 2022-07-06 | — | — | EP | disclosed |
| EP-3543240-B1 | URAT1 INHIBITOR AND USE THEREOF | JIANGSU ATOM BIOSCIENCE AND PHARMACEUTICAL CO LTD (CN) | 2022-07-06 | — | — | EP | disclosed |
| EP-3543240-A1 | URAT1 INHIBITOR AND USE THEREOF | Jiangsu Atom Bioscience And Pharmaceutical Co., Ltd. (CN) | 2019-09-25 | — | — | EP | disclosed |
| EP-3543240-A1 | URAT1 INHIBITOR AND USE THEREOF | Jiangsu Atom Bioscience And Pharmaceutical Co., Ltd. (CN) | 2019-09-25 | — | — | EP | disclosed |
| WO-2018090921-A1 | URAT1 INHIBITOR AND USE THEREOF | 江苏新元素医药科技有限公司 | 2018-05-24 | — | — | WO | disclosed |