Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RHEB | Q15382 | 7/20 | 0.56 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTR1B | P28222 | 2/20 | 0.40 |
| ▸ | BRAF | P15056 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 4/20 | 0.39 |
| ▸ | DRD4 | P21917 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1499400 | 0.76 | RHEB (0.73) | RHEBTRPA1MEN1MAPK1KMT2A | |
| SCHEMBL4716647 | 0.75 | RHEB (0.69) | RHEBTRPA1MEN1MAPK1KMT2A | |
| SCHEMBL9687165 | 0.72 | RHEB (0.55) | RHEBTRPA1MEN1MAPK1KMT2A | |
| SCHEMBL20535840 | 0.72 | RHEB (1.00) | RHEBTRPA1HTR1ASLC6A3 | |
| SCHEMBL20536163 | 0.72 | RHEB (0.68) | RHEBTRPA1MEN1MAPK1KMT2A | |
| SCHEMBL12925129 | 0.72 | MMP12 (0.56) | MEN1MAPK1KMT2AEGFRAPP | |
| SCHEMBL31200193 | 0.72 | MMP12 (0.56) | MEN1MAPK1KMT2AEGFRAPP | |
| SCHEMBL9047954 | 0.71 | RHEB (0.72) | RHEBTRPA1MEN1MAPK1KMT2A | |
| SCHEMBL13915642 | 0.71 | RHEB (0.59) | RHEBTRPA1MEN1MAPK1KMT2A | |
| SCHEMBL31156705 | 0.70 | RHEB (0.53) | RHEBTRPA1MEN1MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018093968-A1 | IMIDAZOPYRIDAZINE MODULATORS OF IL-12, IL-23 AND/OR IFN-ALPHA | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-05-24 | — | — | WO | disclosed |