Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | MMP14 | P50281 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10721636 | 0.79 | KDM4E (0.42) | KDM4EALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL12212081 | 0.76 | ALDH1A1 (0.47) | KDM4EALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL20152570 | 0.76 | KDM4E (0.44) | KDM4EALDH1A1L3MBTL1LMNAPOLB | |
| SCHEMBL31482558 | 0.75 | KDM4E (0.57) | KDM4EALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL10786887 | 0.75 | KDM4E (0.57) | KDM4EALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL31506337 | 0.74 | CA12 (0.49) | KDM4EALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL28654700 | 0.74 | ALDH1A1 (0.46) | KDM4EALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL20160700 | 0.73 | KDM4E (0.41) | KDM4EALDH1A1L3MBTL1LMNAPOLB | |
| SCHEMBL19743195 | 0.72 | KDM4E (0.46) | KDM4EALDH1A1L3MBTL1LMNAPOLB | |
| SCHEMBL1244976 | 0.72 | KDM4E (0.53) | KDM4EALDH1A1L3MBTL1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190352318-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2019-11-21 | — | — | US | disclosed |
| WO-2018091435-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2018-05-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190352318-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | L1CAM, EFNA1, EPCAM | KDM4E 3088/4885ALDH1A1 33/4885L3MBTL1 2243/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.