Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCL8 | P10145 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28780309 | 1.00 | CXCL8 (0.54) | CXCL8NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL28122217 | 0.98 | CXCL8 (0.53) | CXCL8NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL28847313 | 0.98 | CXCL8 (0.53) | CXCL8NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL28307658 | 0.98 | CXCL8 (0.53) | CXCL8NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL5692314 | 0.85 | PARP1 (0.51) | CXCL8RAB9ASMN1; SMN2ALDH1A1GAA | |
| SCHEMBL188545 | 0.85 | PARP1 (0.46) | CXCL8NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL7850943 | 0.84 | RAB9A (0.47) | CXCL8NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL5966407 | 0.83 | ALB (0.47) | CXCL8NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL23361657 | 0.82 | ALDH1A1 (0.54) | CXCL8NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL30093188 | 0.82 | ALDH1A1 (0.54) | CXCL8NPC1RAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 651 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020018839-A1 | COMPOUNDS AND METHODS FOR SYNERGISTIC ACTIVATION OF M CHANNELS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-01-23 | — | — | WO | claimed |
| CN-109912439-A | Method for continuously and rapidly preparing DL-phenylglycine and analogue thereof by using cyanohydrin method | 禄丰天宝磷化工有限公司 | 2019-06-21 | — | — | CN | claimed |
| CN-109824531-A | Method for continuously and rapidly preparing DL-phenylglycine and analogues thereof | 禄丰天宝磷化工有限公司 | 2019-05-31 | — | — | CN | claimed |
| CN-106442787-B | The foundation of liquid chromatogram retention index and its application in terms of compound characterization | 中国烟草总公司郑州烟草研究院 | 2019-04-12 | — | — | CN | claimed |
| CN-105237458-B | A kind of preparation method of polysubstituted indole derivatives | 上海应用技术学院 | 2018-01-26 | — | — | CN | claimed |
| CN-104958286-B | For treating the compound of disease | 伊诺克西亚生命科学股份有限公司 | 2018-01-05 | — | — | CN | claimed |
| CN-105669618-A | Preparation method of polysubstituted benzofuran derivative | 上海应用技术学院 | 2016-06-15 | — | — | CN | claimed |
| EP-2965755-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF DISEASES | Inoxia Lifesciences GmbH (AT) | 2016-01-13 | — | — | EP | claimed |
| CN-105237458-A | Preparation method for polysubstituted indole derivatives | SHANGHAI INST TECHNOLOGY | 2016-01-13 | — | — | CN | claimed |
| CN-104958286-A | Compounds for use in the treatment of diseases | INOXIA LIFESCIENCES GMBH | 2015-10-07 | — | — | CN | claimed |
| WO-2011091461-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF DISEASES | PLANTA NATURSTOFFE VERTRIEBSGES.M.B.H. (AT) | 2011-08-04 | — | — | WO | claimed |
| CN-101565380-A | Preparation method of L(+)-p-fluorophenyl glycine | JIANGSU ALPHA PHARMACEUTICAL C (CN) | 2009-10-28 | — | — | CN | claimed |
| CN-101368199-A | Method for preparing D-aminophenol with immobilization penicillin acylated enzyme catalysis | UNIV CHONGQING POSTS & TELECOM (CN) | 2009-02-18 | — | — | CN | claimed |
| CN-101003822-A | Method for producing D amino acid by immobilizing acylation enzyme of penicillin | CHENGDU ORGANIC CHEMISTRY C A (CN) | 2007-07-25 | — | — | CN | claimed |
| EP-1735312-A1 | SUBSTITUTED DIAZA-SPIRO-[5.5|-UNDECANE DERIVATIVES AND THEIR USE AS NEUROKININ ANTAGONISTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-12-27 | — | — | EP | claimed |
| WO-2005097795-A1 | SUBSTITUTED DIAZA-SPIRO-[5.5]-UNDECANE DERIVATIVES AND THEIR USE AS NEUROKININ ANTAGONISTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-10-20 | — | — | WO | claimed |
| EP-1276732-A1 | AMIDES OF R-2-(AMINOARYL)-PROPIONIC ACIDS FOR USE IN THEPREVENTION OF LEUCOCYTE ACTIVATION\ | Dompé S.P.A. (IT) | 2003-01-22 | — | — | EP | claimed |
| WO-2001079189-A2 | 'AMIDES OF R-2-(AMINOARYL)-PROPIONIC ACIDS FOR USE IN THEPREVENTION OF LEUCOCYTE ACTIVATION' | Dompé S.p.A. (IT) | 2001-10-25 | — | — | WO | claimed |
| EP-0920307-A2 | DERIVATES FROM BISARYLTETRACARBONACID, AND PHARMARCEUTICAL PRODUCT CONTAINING THEM | Roche Diagnostics GmbH (DE) | 1999-06-09 | — | — | EP | claimed |
| WO-1998006386-A2 | DERIVATES FROM BISARYLTETRACARBONACID, AND PHARMARCEUTICAL PRODUCT CONTAINING THEM | ROCHE DIAGNOSTICS GMBH (DE) | 1998-02-19 | — | — | WO | claimed |