Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12636281 | 0.89 | SMN1; SMN2 (0.38) | ADORA2AMAPTNPC1MEN1RAB9A | |
| SCHEMBL12635938 | 0.88 | MAPT (0.46) | MAPTNPC1RAB9ANLRP3ACSS2 | |
| SCHEMBL2014866 | 0.86 | SMN1; SMN2 (0.52) | MAPTGAANPC1MEN1RAB9A | |
| SCHEMBL2016915 | 0.85 | MAPT (0.46) | MAPTNPC1RAB9ANLRP3SMN1; SMN2 | |
| SCHEMBL12635742 | 0.84 | CHEK2 (0.41) | ADORA2AMAPTNPC1MEN1KMT2A | |
| SCHEMBL2016331 | 0.83 | HTT (0.52) | MAPTGAANPC1MEN1KMT2A | |
| SCHEMBL12635727 | 0.79 | ALDH1A1 (0.36) | ADORA2AMAPTGAANPC1MEN1 | |
| SCHEMBL2017353 | 0.79 | MAPT (0.52) | MAPTNPC1RAB9ANLRP3NPSR1 | |
| Iodide SCHEMBL2021861 | 0.79 | KDM4E (0.35) | ADORA2AMAPTGAAMEN1KMT2A | |
| Iodide SCHEMBL2018595 | 0.78 | DRD5 (0.39) | ADORA2AMAPTGAANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011079087-A1 | ENAC BLOCKERS | GLAXO GROUP LIMITED (GB) | 2011-06-30 | — | — | WO | disclosed |
| WO-2011079087-A1 | ENAC BLOCKERS | GLAXO GROUP LIMITED (GB) | 2011-06-30 | — | — | WO | disclosed |