Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 3/20 | 0.41 |
| ▸ | TLR2 | O60603 | 1/20 | 0.41 |
| ▸ | ERN1 | O75460 | 1/20 | 0.41 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.41 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20151862 | 0.81 | ERN1 (0.38) | ALDH1A1LMNACYP2C9CYP2C19HPGD | |
| SCHEMBL20570798 | 0.80 | ERN1 (0.39) | ALDH1A1LMNAHPGDSMN1; SMN2SRC | |
| SCHEMBL18322562 | 0.80 | SMN1; SMN2 (0.46) | ALDH1A1LMNAPTGDR2HPGDHTT | |
| SCHEMBL15397098 | 0.80 | ADAM17 (0.40) | ALDH1A1LMNAHPGDHTTSMN1; SMN2 | |
| SCHEMBL26123722 | 0.80 | KMT2A (0.38) | ALDH1A1LMNAHPGDHTTSMN1; SMN2 | |
| SCHEMBL26126678 | 0.78 | HPGD (0.40) | ALDH1A1LMNAHPGDHTTSMN1; SMN2 | |
| SCHEMBL20137021 | 0.77 | KDM4E (0.39) | ALDH1A1CYP1A2CYP2C9CYP2C19HPGD | |
| SCHEMBL2428471 | 0.76 | ERN1 (0.40) | ALDH1A1PTGDR2HPGDERN1KMT2A | |
| SCHEMBL18322694 | 0.75 | CYP2D6 (0.40) | ALDH1A1HPGDKMT2AGAAMEN1 | |
| SCHEMBL31421785 | 0.75 | MEN1 (0.43) | ALDH1A1PTGDR2HPGDKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018093949-A1 | MAGL INHIBITORS | ABIDE THERAPEUTICS, INC. (US) | 2018-05-24 | — | — | WO | disclosed |