Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | POLA1 | P09884 | 2/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20570798 | 0.85 | ERN1 (0.39) | ERN1ALDH1A1SRCPOLA1HPGD | |
| SCHEMBL20137021 | 0.82 | KDM4E (0.39) | ALDH1A1MAPTCYP2C9CYP2C19HSD17B10 | |
| SCHEMBL20182572 | 0.81 | ALDH1A1 (0.43) | ERN1ALDH1A1SRCCYP2C9CYP2C19 | |
| SCHEMBL31645176 | 0.81 | KMT2A (0.37) | LPAR1MAPTCYP3A4CYP2C9PKM | |
| SCHEMBL22116340 | 0.76 | LPAR1 (0.37) | LPAR1CYP3A4CYP2C9PKMCYP2C19 | |
| SCHEMBL13847857 | 0.74 | HPGD (0.42) | ALDH1A1LPAR1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL22116318 | 0.74 | PTGDR2 (0.46) | ALDH1A1LPAR1PKMHPGDSMN1; SMN2 | |
| SCHEMBL2428471 | 0.73 | ERN1 (0.40) | ERN1ALDH1A1POLA1MAPTPKM | |
| SCHEMBL22116398 | 0.72 | SLC9A3 (0.33) | SRCCYP2C9NPSR1LMNAL3MBTL1 | |
| SCHEMBL96209 | 0.71 | ALDH1A1 (0.66) | ERN1ALDH1A1MAPTCYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11691975-B2 | MAGL inhibitors | H. LUNDBECKA/S (DK) | 2023-07-04 | — | — | US | disclosed |
| US-20180134674-A1 | MAGL INHIBITORS | H. LUNDBECK A/S (DK) | 2018-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180134674-A1 | MAGL INHIBITORS | MAG, MAGI3, MGLL | ERN1 3681/4885ALDH1A1 4349/4885SRC 3069/4885 |
| US-11691975-B2 | MAGL inhibitors | MAG, MAGI3, MGLL | ERN1 2045/4885ALDH1A1 4002/4885SRC 2176/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.