SCHEMBL18322694

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18322710	0.82	SMN1; SMN2 (0.46)	ALDH1A1MEN1KMT2ATSHRKCNH2
	SCHEMBL30890728	0.79	BACE1 (0.42)	CYP2D6CTSDHPGDALDH1A1KDM4E
	SCHEMBL26123722	0.78	KMT2A (0.38)	HPGDALDH1A1KDM4EGAANPC1
	SCHEMBL15397098	0.78	ADAM17 (0.40)	HPGDALDH1A1KDM4EMEN1KMT2A
	SCHEMBL26126678	0.77	HPGD (0.40)	HPGDALDH1A1GAANPC1MEN1
	SCHEMBL18322478	0.77	CPB2 (0.37)	CYP2D6HPGDMEN1KMT2ATSHR
	SCHEMBL20182572	0.75	ALDH1A1 (0.43)	HPGDALDH1A1KDM4EGAANPC1
	SCHEMBL31421785	0.73	MEN1 (0.43)	HPGDALDH1A1KDM4EGAAMEN1
	SCHEMBL26124155	0.73	MEN1 (0.43)	HPGDALDH1A1KDM4EGAAMEN1
	SCHEMBL22513459	0.73	ITGA4 (0.33)	CYP2D6MEN1KMT2ATSHRKCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.