Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 16/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 16/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20182758 | 0.92 | POLB (0.44) | POLBGRIN1GRIN2BPTGS2USP2 | |
| SCHEMBL20182759 | 0.89 | POLB (0.43) | POLBGRIN1GRIN2BPTGS2 | |
| SCHEMBL21641516 | 0.86 | POLB (0.45) | POLBUSP2ALDH1A1CYP1A2CLK4 | |
| SCHEMBL14684583 | 0.86 | POLB (0.48) | POLBALDH1A1 | |
| SCHEMBL29360277 | 0.86 | POLB (0.48) | POLBALDH1A1 | |
| SCHEMBL18866344 | 0.86 | POLB (0.42) | POLBGRIN1GRIN2BPTGS2ALDH1A1 | |
| SCHEMBL15868301 | 0.83 | POLB (0.46) | POLBALDH1A1 | |
| SCHEMBL25885629 | 0.83 | POLB (0.39) | POLBGRIN1GRIN2B | |
| SCHEMBL30989728 | 0.83 | POLB (0.39) | POLBGRIN1GRIN2B | |
| SCHEMBL25888089 | 0.82 | POLB (0.38) | POLBGRIN1GRIN2BPTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018091389-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-05-24 | — | — | WO | disclosed |