Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | DDR1 | Q08345 | 7/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.31 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29360277 | 0.93 | POLB (0.48) | POLBDDR1LRRK2ALOX5APFEN1 | |
| SCHEMBL14684583 | 0.93 | POLB (0.48) | POLBDDR1LRRK2ALOX5APFEN1 | |
| SCHEMBL15868301 | 0.90 | POLB (0.46) | POLBDDR1LRRK2ALOX5APFEN1 | |
| SCHEMBL20182758 | 0.89 | POLB (0.44) | POLBDDR1ALOX5APFEN1MEN1 | |
| SCHEMBL16376050 | 0.88 | POLB (0.45) | POLBDDR1LRRK2ALOX5APFEN1 | |
| SCHEMBL21641644 | 0.88 | POLB (0.45) | POLBDDR1LRRK2MEN1ALDH1A1 | |
| SCHEMBL29431660 | 0.88 | POLB (0.45) | POLBDDR1LRRK2ALOX5APFEN1 | |
| SCHEMBL14684615 | 0.88 | POLB (0.45) | POLBDDR1LRRK2ALOX5APFEN1 | |
| SCHEMBL29431643 | 0.88 | POLB (0.45) | POLBDDR1LRRK2ALOX5APFEN1 | |
| SCHEMBL14677420 | 0.88 | POLB (0.45) | POLBDDR1LRRK2ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110461834-B | Condensed heterocyclic compound and composition containing same | 住友化学株式会社 | 2024-03-12 | — | — | CN | disclosed |
| EP-3604300-B1 | FUSED HETEROCYCLIC COMPOUND AND COMPOSITION CONTAINING SAME | SUMITOMO CHEMICAL CO (JP) | 2022-06-01 | — | — | EP | disclosed |
| US-10934287-B2 | Fused heterocyclic compound and composition containing same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2021-03-02 | — | — | US | disclosed |
| US-20200071320-A1 | FUSED HETEROCYCLIC COMPOUND AND COMPOSITION CONTAINING SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2020-03-05 | — | — | US | disclosed |
| EP-3604300-A1 | FUSED HETEROCYCLIC COMPOUND AND COMPOSITION CONTAINING SAME | Sumitomo Chemical Company, Limited (JP) | 2020-02-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10934287-B2 | Fused heterocyclic compound and composition containing same | SDHA, SDHB, CYP4X1 | POLB 3682/4885DDR1 4814/4885LRRK2 1352/4885 |
| US-20200071320-A1 | FUSED HETEROCYCLIC COMPOUND AND COMPOSITION CONTAINING SAME | SDHA, SDHB, CYP4X1 | POLB 3682/4885DDR1 4814/4885LRRK2 1352/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.