Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 2/20 | 0.36 |
| ▸ | CASP7 | P55210 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 8/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 7/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20182714 | 0.92 | POLB (0.40) | POLBCYP1A2ALDH1A1CLK4USP2 | |
| SCHEMBL20182759 | 0.89 | POLB (0.43) | POLBGRIN2BGRIN1DDR1ALOX5AP | |
| SCHEMBL21641516 | 0.89 | POLB (0.45) | POLBCYP1A2MEN1ALDH1A1KMT2A | |
| SCHEMBL14684583 | 0.89 | POLB (0.48) | POLBMEN1ALDH1A1KMT2ADDR1 | |
| SCHEMBL29360277 | 0.89 | POLB (0.48) | POLBMEN1ALDH1A1KMT2ADDR1 | |
| SCHEMBL18866344 | 0.86 | POLB (0.42) | POLBMEN1ALDH1A1KMT2AGRIN2B | |
| SCHEMBL15868301 | 0.86 | POLB (0.46) | POLBMEN1ALDH1A1KMT2ADDR1 | |
| SCHEMBL17696194 | 0.86 | CYP1A2 (0.34) | CYP1A2MEN1ALDH1A1KMT2ACLK4 | |
| SCHEMBL16376050 | 0.84 | POLB (0.45) | POLBMEN1ALDH1A1KMT2ADDR1 | |
| SCHEMBL21641644 | 0.84 | POLB (0.45) | POLBMEN1ALDH1A1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018091389-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-05-24 | — | — | WO | disclosed |