Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | DDR1 | Q08345 | 6/20 | 0.32 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
| ▸ | IDH2 | P48735 | 1/20 | 0.32 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17696232 | 0.89 | NPC1 (0.33) | NPC1MAPTIDH1IDH2PRMT6 | |
| SCHEMBL29360277 | 0.85 | POLB (0.48) | POLBNPC1DDR1 | |
| SCHEMBL14684583 | 0.85 | POLB (0.48) | POLBNPC1DDR1 | |
| SCHEMBL20165435 | 0.84 | POLB (0.40) | POLBDDR1 | |
| SCHEMBL17553650 | 0.84 | NPC1 (0.33) | NPC1MAPTIDH1IDH2PRMT6 | |
| SCHEMBL20165440 | 0.83 | POLB (0.42) | POLBNPC1MAPTIDH1IDH2 | |
| SCHEMBL17640652 | 0.83 | PDE2A (0.33) | IDH1 | |
| SCHEMBL15868301 | 0.82 | POLB (0.46) | POLBNPC1DDR1 | |
| SCHEMBL20636713 | 0.82 | POLB (0.36) | POLBNPC1MAPTPTGS1PTGS2 | |
| SCHEMBL21641516 | 0.81 | POLB (0.45) | POLBNPC1DDR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018091389-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-05-24 | — | — | WO | disclosed |