Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 4/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.30 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.30 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
| ▸ | IDH1 | O75874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17640464 | 0.85 | PDE2A (0.32) | PDE2ALRRK2PDE10A | |
| SCHEMBL17696232 | 0.83 | NPC1 (0.33) | PDE10AIDH1 | |
| SCHEMBL17633968 | 0.83 | LRRK2 (0.35) | PDE2ALRRK2 | |
| SCHEMBL17640658 | 0.83 | PDE2A (0.36) | PDE2ALRRK2 | |
| SCHEMBL20182715 | 0.83 | POLB (0.39) | IDH1 | |
| SCHEMBL17640473 | 0.83 | LRRK2 (0.34) | PDE2ALRRK2HCRTR1HCRTR2 | |
| SCHEMBL17640665 | 0.81 | PDE2A (0.35) | PDE2ALRRK2 | |
| SCHEMBL17640666 | 0.80 | CYP1A2 (0.33) | LRRK2 | |
| SCHEMBL17553650 | 0.79 | NPC1 (0.33) | PDE10AIDH1 | |
| SCHEMBL18915171 | 0.77 | CNR2 (0.33) | IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016046071-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-03-31 | — | — | WO | disclosed |