Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 14/20 | 0.73 |
| ▸ | BACE1 | P56817 | 13/20 | 0.73 |
| ▸ | ACHE | P22303 | 12/20 | 0.73 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8576045 | 1.00 | BCHE (0.73) | BCHEBACE1ACHECXCR4 | |
| SCHEMBL31015505 | 0.91 | BCHE (0.61) | BCHEBACE1ACHECXCR4 | |
| SCHEMBL31014655 | 0.87 | BCHE (0.61) | BCHEBACE1ACHE | |
| SCHEMBL31014995 | 0.86 | BCHE (0.58) | BCHEBACE1ACHE | |
| SCHEMBL9437321 | 0.85 | ACHE (0.60) | BCHEBACE1ACHECXCR4 | |
| SCHEMBL3311538 | 0.85 | ACHE (0.68) | BCHEBACE1ACHECXCR4 | |
| SCHEMBL4131291 | 0.84 | ACHE (1.00) | BCHEBACE1ACHE | |
| SCHEMBL5692288 | 0.84 | ACHE (1.00) | BCHEBACE1ACHE | |
| SCHEMBL28169202 | 0.84 | CXCR4 (0.68) | BCHEBACE1ACHECXCR4 | |
| SCHEMBL8186709 | 0.84 | ACHE (0.66) | BCHEBACE1ACHECXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108137608-B | Janus kinase 1 selective inhibitor and pharmaceutical application thereof | 阳智化学（株） | 2020-06-19 | — | — | CN | disclosed |
| US-10407430-B2 | Janus kinase 1 selective inhibitor and pharmaceutical use thereof | YANG JI CHEMICAL CO., LTD. (KR) | 2019-09-10 | — | — | US | disclosed |
| US-20180237440-A1 | JANUS KINASE 1 SELECTIVE INHIBITOR AND PHARMACEUTICAL USE THEREOF | YANG JI CHEMICAL CO., LTD. (KR) | 2018-08-23 | — | — | US | disclosed |
| EP-3327021-A1 | JANUS KINASE 1 SELECTIVE INHIBITOR AND PHARMACEUTICAL USE THEREOF | Yangji Chemical Co., Ltd. (KR) | 2018-05-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10407430-B2 | Janus kinase 1 selective inhibitor and pharmaceutical use thereof | JAK1, JAK2, JAK3 | BCHE 4529/4885BACE1 2664/4885ACHE 4882/4885 |
| US-20180237440-A1 | JANUS KINASE 1 SELECTIVE INHIBITOR AND PHARMACEUTICAL USE THEREOF | JAK1, JAK2, JAK3 | BCHE 3320/4885BACE1 1988/4885ACHE 4872/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.