Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | ADH1B | P00325 | 1/20 | 0.32 |
| ▸ | ADH1C | P00326 | 1/20 | 0.32 |
| ▸ | ADH1A | P07327 | 1/20 | 0.32 |
| ▸ | ADH7 | P40394 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL133787 | 0.95 | — | — | |
| SCHEMBL25800877 | 0.95 | — | — | |
| SCHEMBL133775 | 0.92 | — | — | |
| SCHEMBL1199958 | 0.87 | ALDH1A1 (0.46) | TSHREPHX1ALDH1A1KDM4EALOX15 | |
| SCHEMBL4209196 | 0.87 | LMNA (0.36) | TSHRALDH1A1KDM4ELMNACNR1 | |
| SCHEMBL5790232 | 0.87 | ALDH1A1 (0.36) | TSHREPHX1ALDH1A1KDM4EALOX15 | |
| SCHEMBL16390572 | 0.85 | EPHX1 (0.46) | TSHREPHX1ALDH1A1KDM4EALOX15 | |
| SCHEMBL9016915 | 0.85 | EPHX1 (0.46) | TSHREPHX1ALDH1A1KDM4EALOX15 | |
| SCHEMBL16390218 | 0.85 | EPHX1 (0.46) | TSHREPHX1ALDH1A1KDM4EALOX15 | |
| SCHEMBL16390227 | 0.85 | EPHX1 (0.46) | TSHREPHX1ALDH1A1KDM4EALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3325423-A1 | NOVEL SHRINKAGE-REDUCING AGENTS FOR MINERAL BINDERS | Evonik Degussa GmbH (DE) | 2018-05-30 | — | — | EP | disclosed |