SCHEMBL4209196

SCHEMBL4209196

CCC(O)NCCCNC(O)CC

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.36
KDM4E B2RXH2 2/20 0.36
CNR1 P21554 1/20 0.36
ADRA1A P35348 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
TSHR P16473 3/20 0.35
ABCC3 O15438 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
ALDH1A1 P00352 2/20 0.32
MEN1 O00255 1/20 0.30
GLA P06280 1/20 0.30
CYP2C19 P33261 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5790232 0.94 ALDH1A1 (0.36) LMNAKDM4ECNR1ADRA1ATDP1
SCHEMBL4205138 0.92 ALDH1A1 (0.39) LMNAKDM4ECNR1ADRA1ATDP1
SCHEMBL4201284 0.92 ALDH1A1 (0.39) LMNAKDM4ECNR1ADRA1ATDP1
SCHEMBL133787 0.92
SCHEMBL25800877 0.92
SCHEMBL1199958 0.89 ALDH1A1 (0.46) LMNAKDM4EADRA1ATSHRSMN1; SMN2
SCHEMBL4199276 0.88 LMNA (0.46) LMNAKDM4ECNR1ADRA1ATDP1
SCHEMBL16390247 0.87 EPHX1 (0.46) LMNAKDM4EADRA1ATSHRSMN1; SMN2
SCHEMBL16390227 0.87 EPHX1 (0.46) LMNAKDM4EADRA1ATSHRSMN1; SMN2
SCHEMBL16390218 0.87 EPHX1 (0.46) LMNAKDM4EADRA1ATSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1828354-B1 HYDROCARBYL SUCCINIC ACID AND HYDROCARBYLSUCCINIC ACID DERIVATIVES AS FRICTION MODIFIERS BASF SE (DE) 2017-09-06 EP disclosed
US-20090235576-A1 HYDROCARBYL SUCCINIC ACID AND HYDROCARBYLSUCCINIC ACID DERIVATIVES AS FRICTION MODIFIERS BASF AKTIENGESELLSCHAFT (DE) 2009-09-24 US disclosed
EP-1828354-A1 HYDROCARBYL SUCCINIC ACID AND HYDROCARBYLSUCCINIC ACID DERIVATIVES AS FRICTION MODIFIERS BASF AKTIENGESELLSCHAFT (DE) 2007-09-05 EP disclosed
WO-2006063770-A1 HYDROCARBYL SUCCINIC ACID AND HYDROCARBYLSUCCINIC ACID DERIVATIVES AS FRICTION MODIFIERS BASF AKTIENGESELLSCHAFT (DE) 2006-06-22 WO disclosed
EP-1669433-A1 Hydrocarbyl succinic acid and hydrocarbylsuccinic acid derivatives as friction modifiers BASF AKTIENGESELLSCHAFT (DE) 2006-06-14 EP disclosed