Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.43 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.41 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.41 |
| ▸ | ESRRG | P62508 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15296549 | 0.81 | MAP2K1 (0.42) | MAPTSMN1; SMN2TP53RAB9APTGDR2 | |
| SCHEMBL4620600 | 0.81 | CES2 (0.46) | MAPTSMN1; SMN2TP53RAB9APTGDR2 | |
| SCHEMBL108796 | 0.81 | SMN1; SMN2 (0.47) | MAPTSMN1; SMN2TP53RAB9APTGDR2 | |
| SCHEMBL18398755 | 0.81 | SMN1; SMN2 (0.45) | MAPTSMN1; SMN2TP53RAB9APTGDR2 | |
| SCHEMBL107636 | 0.80 | CSNK2A1 (0.52) | MAPTSMN1; SMN2TP53RAB9AALDH1A1 | |
| SCHEMBL28471721 | 0.80 | CES2 (0.48) | MAPTSMN1; SMN2TP53RAB9APTGDR2 | |
| SCHEMBL3139113 | 0.80 | ALDH1A1 (0.46) | MAPTALDH1A1GFERCES2TMPRSS4 | |
| SCHEMBL2634026 | 0.80 | KDM4E (0.62) | MAPTSMN1; SMN2TP53RAB9AALDH1A1 | |
| SCHEMBL16520931 | 0.80 | SMN1; SMN2 (0.40) | MAPTSMN1; SMN2TP53RAB9APTGDR2 | |
| SCHEMBL15296546 | 0.80 | RAB9A (0.43) | MAPTSMN1; SMN2TP53RAB9APTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3325446-A1 | SUBSTITUTED ARYL AND HETEROARYL CARBOXYLIC ACID HYDRAZIDES OR SALTS THEREOF AND USE THEREOF TO INCREASE STRESS TOLERANCE IN PLANTS | Bayer CropScience Aktiengesellschaft (DE) | 2018-05-30 | — | — | EP | disclosed |