Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 6/20 | 0.49 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.49 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | ANPEP | P15144 | 1/20 | 0.46 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.46 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.44 |
| ▸ | ITGA5 | P08648 | 3/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3669498 | 0.90 | ALDH1A1 (0.56) | S1PR1S1PR3S1PR2ALDH1A1HDAC3 | |
| SCHEMBL8420591 | 0.86 | ALDH1A1 (0.68) | S1PR1S1PR3S1PR2ALDH1A1HDAC3 | |
| SCHEMBL11508408 | 0.85 | TPSAB1 (0.55) | S1PR1S1PR3S1PR2ALDH1A1ANPEP | |
| SCHEMBL18459808 | 0.85 | KDM4E (0.52) | ALDH1A1ANPEPERAP2ITGB1ITGA5 | |
| Lithium SCHEMBL11511589 | 0.84 | TPSAB1 (0.53) | S1PR1S1PR3S1PR2ALDH1A1ANPEP | |
| SCHEMBL3187395 | 0.83 | S1PR1 (0.50) | S1PR1S1PR3S1PR2ALDH1A1HDAC3 | |
| SCHEMBL2224632 | 0.82 | MEN1 (0.64) | S1PR1ALDH1A1HDAC3HDAC1HDAC2 | |
| SCHEMBL12072934 | 0.81 | ALDH1A1 (0.61) | S1PR1S1PR3S1PR2ALDH1A1HDAC8 | |
| SCHEMBL3207348 | 0.81 | S1PR1 (0.60) | S1PR1S1PR3S1PR2ALDH1A1HDAC3 | |
| SCHEMBL5940017 | 0.81 | HTT (0.62) | S1PR1S1PR3S1PR2ALDH1A1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2096912-B1 | FORMULATIONS AND USES OF 2-HYDROXY-5-PHENYLAZOBENZOIC ACID DERIVATIVES | SALIX PHARMACEUTICALS INC (US) | 2018-05-30 | — | — | EP | disclosed |