SCHEMBL20184822

SCHEMBL20184822

O=P(O)(O)OP(=O)(O)Oc1c(Br)cc(Br)cc1Br

nearest known ligand 0.37

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.37
INPPL1 O15357 6/20 0.35
INPP5A Q14642 4/20 0.35
INPP5B P32019 1/20 0.35
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
TDP1 Q9NUW8 2/20 0.33
SRC P12931 2/20 0.33
BTN3A1 O00481 1/20 0.33
CYP3A4 P08684 1/20 0.33
TSHR P16473 1/20 0.33
ERN1 O75460 1/20 0.33
FDPS P14324 1/20 0.33
BLM P54132 1/20 0.33
MCHR1 Q99705 1/20 0.33
ALOX15 P16050 3/20 0.33
ALOX12 P18054 2/20 0.33
AKT1 P31749 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28736776 0.88 HSD17B10 (0.41) HSD17B10INPPL1INPP5AINPP5BMEN1
SCHEMBL1901599 0.88 HSD17B10 (0.41) HSD17B10INPPL1INPP5AINPP5BMEN1
SCHEMBL9504804 0.84 INPPL1 (0.48) HSD17B10INPPL1INPP5AINPP5BMEN1
SCHEMBL27525487 0.82 INPPL1 (0.47) HSD17B10INPPL1INPP5AINPP5BMEN1
SCHEMBL28490455 0.75 HSD17B10 (0.37) HSD17B10MEN1KMT2ATDP1CYP3A4
SCHEMBL544825 0.74 HSD17B10 (0.39) HSD17B10MEN1KMT2ATDP1CYP3A4
SCHEMBL10684774 0.72 FDPS (0.36) INPPL1INPP5ATDP1FDPSBLM
SCHEMBL11586247 0.71 HSD17B10 (0.41) HSD17B10INPPL1MEN1KMT2ATDP1
SCHEMBL29893206 0.71 HSD17B10 (0.37) HSD17B10MEN1KMT2ATDP1CYP3A4
SCHEMBL4179025 0.71 TDP1 (0.40) INPPL1INPP5AINPP5BTDP1SRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107722913-B Chloroprene rubber modified flame-retardant polyurethane sealant and preparation method thereof 广东普赛达密封粘胶有限公司 2020-12-04 CN claimed
EP-2617474-B1 FIRE EXTINGUISHING COMPOSITION GENERATING FIRE EXTINGUISHING SUBSTANCE THROUGH HIGH-TEMPERATURE DECOMPOSITION XIAN WESTPEACE FIRE TECH CO LTD (CN) 2020-04-29 EP claimed
EP-2617473-B1 COMPOSITION GENERATING FIRE EXTINGUISHING SUBSTANCE THROUGH CHEMICAL REACTION OF INGREDIENT AT HIGH TEMPERATURE XIAN WESTPEACE FIRE TECH CO LTD (CN) 2018-05-30 EP claimed
CN-114213823-B Preparation method of flame-retardant impact-resistant PLA composite material 上海日之升科技有限公司 2023-11-28 CN disclosed
CN-114213823-A Preparation method of flame-retardant impact-resistant PLA composite material 上海日之升科技有限公司 2022-03-22 CN disclosed
CN-107722913-B Chloroprene rubber modified flame-retardant polyurethane sealant and preparation method thereof 广东普赛达密封粘胶有限公司 2020-12-04 CN disclosed