Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRB1ADRB2ADRB3CYP11B1DPP4FGFR1FGFR2FGFR3FGFR4HRH1JAK1JAK2JAK3KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITNAOPRD1OPRK1OPRM1PPDGFRBPIK3CDSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASMOTYK2polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | INPPL1 | O15357 | 2/20 | 0.36 |
| ▸ | INPP5A | Q14642 | 2/20 | 0.36 |
| ▸ | INPP5B | P32019 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 5/20 | 0.36 |
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MMP14 | P50281 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5007856 | 0.82 | CA2 (0.42) | CYP3A4TSHRTDP1INPPL1INPP5A | |
| Phosphoric Acid SCHEMBL29010694 | 0.82 | CA1 (0.53) | MMP2CA14CA1 | |
| Phosphoric Acid SCHEMBL28053709 | 0.82 | CA1 (0.53) | MMP2CA14CA1 | |
| Phosphoric Acid SCHEMBL27804411 | 0.78 | CYP3A4 (0.48) | CYP3A4TSHRTDP1CA1GABRA1 | |
| SCHEMBL20379807 | 0.76 | CA2 (0.42) | CYP3A4TSHRTDP1INPPL1INPP5A | |
| SCHEMBL24617 | 0.76 | — | — | |
| SCHEMBL31526877 | 0.73 | CYP3A4 (0.30) | CYP3A4TSHRTDP1 | |
| Bromobenzene SCHEMBL30916162 | 0.71 | ALDH1A1 (0.65) | TSHRTDP1MMP2CA12MMP9 | |
| Phosphoric Acid SCHEMBL27460 | 0.71 | — | — | |
| Phosphoric Acid SCHEMBL11399479 | 0.71 | CA2 (0.50) | TSHRTDP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107722913-B | Chloroprene rubber modified flame-retardant polyurethane sealant and preparation method thereof | 广东普赛达密封粘胶有限公司 | 2020-12-04 | — | — | CN | claimed |
| EP-2617474-B1 | FIRE EXTINGUISHING COMPOSITION GENERATING FIRE EXTINGUISHING SUBSTANCE THROUGH HIGH-TEMPERATURE DECOMPOSITION | XIAN WESTPEACE FIRE TECH CO LTD (CN) | 2020-04-29 | — | — | EP | claimed |
| EP-2617473-B1 | COMPOSITION GENERATING FIRE EXTINGUISHING SUBSTANCE THROUGH CHEMICAL REACTION OF INGREDIENT AT HIGH TEMPERATURE | XIAN WESTPEACE FIRE TECH CO LTD (CN) | 2018-05-30 | — | — | EP | claimed |
| CN-114213823-B | Preparation method of flame-retardant impact-resistant PLA composite material | 上海日之升科技有限公司 | 2023-11-28 | — | — | CN | disclosed |
| CN-114213823-A | Preparation method of flame-retardant impact-resistant PLA composite material | 上海日之升科技有限公司 | 2022-03-22 | — | — | CN | disclosed |
| CN-107722913-B | Chloroprene rubber modified flame-retardant polyurethane sealant and preparation method thereof | 广东普赛达密封粘胶有限公司 | 2020-12-04 | — | — | CN | disclosed |