Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 4/20 | 0.43 |
| ▸ | THRB | P10828 | 4/20 | 0.43 |
| ▸ | ICMT | O60725 | 2/20 | 0.40 |
| ▸ | ALB | P02768 | 2/20 | 0.40 |
| ▸ | KDM5A | P29375 | 3/20 | 0.40 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
| ▸ | SCD | O00767 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | RGS12 | O14924 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25252028 | 0.97 | THRA (0.40) | THRATHRBICMTALBKDM5A | |
| SCHEMBL17688581 | 0.89 | SCD (0.41) | OPRK1GPR35SCDMEN1APAF1 | |
| SCHEMBL28737637 | 0.89 | SCD (0.41) | OPRK1GPR35SCDMEN1APAF1 | |
| SCHEMBL27708958 | 0.89 | SCD (0.41) | OPRK1GPR35SCDMEN1APAF1 | |
| SCHEMBL14812641 | 0.83 | CYP1A2 (0.38) | THRATHRBCA12CA1CA2 | |
| SCHEMBL14812852 | 0.83 | CYP1A2 (0.38) | THRATHRBCA12CA1CA2 | |
| SCHEMBL28068926 | 0.77 | FFAR1 (0.43) | MEN1APAF1RGS12HSP90AA1MAPK1 | |
| SCHEMBL28825742 | 0.76 | MEN1 (0.43) | OPRK1GPR35MEN1APAF1RGS12 | |
| SCHEMBL28049646 | 0.76 | MEN1 (0.43) | OPRK1GPR35MEN1APAF1RGS12 | |
| SCHEMBL14815952 | 0.76 | MEN1 (0.43) | OPRK1GPR35MEN1APAF1RGS12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180147166-A1 | BENZENE-1,3,5-TRICARBOXAMIDE DERIVATIVES AND USES THEREOF | OHIO STATE INNOVATION FOUNDATION | 2018-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180147166-A1 | BENZENE-1,3,5-TRICARBOXAMIDE DERIVATIVES AND USES THEREOF | POLRMT, POLN, MTREX | THRA 2078/4885THRB 2830/4885ICMT 4682/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.