Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 3/20 | 0.48 |
| ▸ | AR | P10275 | 2/20 | 0.48 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.47 |
| ▸ | IDH1 | O75874 | 4/20 | 0.45 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20186967 | 0.88 | IMPDH2 (0.45) | IMPDH2CYP17A1IDH1SLC22A12PGR | |
| SCHEMBL20186964 | 0.85 | IMPDH2 (0.50) | IMPDH2ARSLC22A12ALDH1A1KMT2A | |
| SCHEMBL20186969 | 0.82 | IMPDH2 (0.48) | IMPDH2SLC22A12ALDH1A1SMN1; SMN2PGR | |
| SCHEMBL20186979 | 0.82 | IMPDH2 (0.48) | IMPDH2SLC22A12ALDH1A1KMT2AHDAC8 | |
| SCHEMBL20187005 | 0.82 | SLC22A12 (0.54) | IMPDH2SLC22A12ALDH1A1 | |
| SCHEMBL31284484 | 0.80 | IMPDH2 (0.46) | IMPDH2SLC22A12ALDH1A1HDAC8PGR | |
| SCHEMBL20186980 | 0.80 | SLC22A12 (0.54) | IMPDH2ARSLC22A12PGR | |
| SCHEMBL20186993 | 0.80 | IMPDH2 (0.46) | IMPDH2SLC22A12ALDH1A1SMN1; SMN2HDAC8 | |
| SCHEMBL20187004 | 0.80 | IMPDH2 (0.46) | IMPDH2SLC22A12ALDH1A1HDAC8PGR | |
| SCHEMBL20186999 | 0.74 | POLB (0.45) | IMPDH2ALDH1A1MAPK1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10905120-B2 | ABA receptor agonists that modulate transpiration | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-02-02 | — | — | US | disclosed |
| US-20180146666-A1 | ABA RECEPTOR AGONISTS THAT MODULATE TRANSPIRATION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2018-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10905120-B2 | ABA receptor agonists that modulate transpiration | ADORA2A, ADORA1, AAK1 | IMPDH2 2394/4885AR 1334/4885CYP17A1 1066/4885 |
| US-20180146666-A1 | ABA RECEPTOR AGONISTS THAT MODULATE TRANSPIRATION | ADORA2A, ADORA1, AAK1 | IMPDH2 2394/4885AR 1334/4885CYP17A1 1066/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.