Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 1/20 | 0.46 |
| ▸ | SGK1 | O00141 | 1/20 | 0.39 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 3/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31284484 | 1.00 | IMPDH2 (0.46) | IMPDH2SGK1P2RY12GAADRD4 | |
| SCHEMBL20186987 | 0.84 | POLB (0.38) | IMPDH2P2RY12GAACYP3A4CYP2C9 | |
| SCHEMBL20186964 | 0.84 | IMPDH2 (0.50) | IMPDH2GAARORCCYP19A1PGR | |
| SCHEMBL20186979 | 0.81 | IMPDH2 (0.48) | IMPDH2GAARORCCYP19A1PGR | |
| SCHEMBL20187005 | 0.81 | SLC22A12 (0.54) | IMPDH2GAABRPF1NPC1ALDH1A1 | |
| SCHEMBL20186969 | 0.81 | IMPDH2 (0.48) | IMPDH2P2RY12GAACYP3A4CYP2C9 | |
| SCHEMBL20186975 | 0.80 | IMPDH2 (0.48) | IMPDH2PGRHDAC8ALDH1A1SLC22A12 | |
| SCHEMBL20186980 | 0.79 | SLC22A12 (0.54) | IMPDH2RORCPGRSLC22A12 | |
| SCHEMBL20186993 | 0.79 | IMPDH2 (0.46) | IMPDH2P2RY12GAACYP3A4CYP2C9 | |
| SCHEMBL20186967 | 0.78 | IMPDH2 (0.45) | IMPDH2SGK1P2RY12CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10905120-B2 | ABA receptor agonists that modulate transpiration | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-02-02 | — | — | US | disclosed |
| US-20180146666-A1 | ABA RECEPTOR AGONISTS THAT MODULATE TRANSPIRATION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2018-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10905120-B2 | ABA receptor agonists that modulate transpiration | ADORA2A, ADORA1, AAK1 | IMPDH2 2394/4885SGK1 1793/4885P2RY12 486/4885 |
| US-20180146666-A1 | ABA RECEPTOR AGONISTS THAT MODULATE TRANSPIRATION | ADORA2A, ADORA1, AAK1 | IMPDH2 2394/4885SGK1 1793/4885P2RY12 486/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.