Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.35 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20186999 | 0.87 | POLB (0.45) | POLBIMPDH2KDM4EALDH1A1HPGD | |
| SCHEMBL20187000 | 0.85 | ALDH1A1 (0.40) | IMPDH2ALDH1A1RORCTSHRNAMPT | |
| SCHEMBL31284484 | 0.84 | IMPDH2 (0.46) | IMPDH2P2RY12ALDH1A1RORCCYP3A4 | |
| SCHEMBL20187004 | 0.84 | IMPDH2 (0.46) | IMPDH2P2RY12ALDH1A1RORCCYP3A4 | |
| SCHEMBL20186966 | 0.82 | POLB (0.41) | POLBIMPDH2KDM4EALDH1A1HPGD | |
| SCHEMBL20186960 | 0.81 | POLB (0.41) | POLBIMPDH2KDM4EALDH1A1HPGD | |
| SCHEMBL20186981 | 0.78 | POLB (0.39) | POLBIMPDH2KDM4EALDH1A1HPGD | |
| SCHEMBL20186984 | 0.77 | ALDH1A1 (0.50) | IMPDH2KDM4EALDH1A1HPGDGPR119 | |
| SCHEMBL20186964 | 0.74 | IMPDH2 (0.50) | IMPDH2ALDH1A1HPGDRORCBRPF1 | |
| SCHEMBL20186979 | 0.68 | IMPDH2 (0.48) | IMPDH2ALDH1A1HPGDRORCBRPF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10905120-B2 | ABA receptor agonists that modulate transpiration | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-02-02 | — | — | US | disclosed |
| US-20180146666-A1 | ABA RECEPTOR AGONISTS THAT MODULATE TRANSPIRATION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2018-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10905120-B2 | ABA receptor agonists that modulate transpiration | ADORA2A, ADORA1, AAK1 | POLB 3901/4885IMPDH2 2394/4885P2RY12 486/4885 |
| US-20180146666-A1 | ABA RECEPTOR AGONISTS THAT MODULATE TRANSPIRATION | ADORA2A, ADORA1, AAK1 | POLB 3901/4885IMPDH2 2394/4885P2RY12 486/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.