Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 6/20 | 0.56 |
| ▸ | ELANE | P08246 | 9/20 | 0.54 |
| ▸ | CTSG | P08311 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.36 |
| ▸ | PRKCI | P41743 | 1/20 | 0.36 |
| ▸ | CTRC | Q99895 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20187585 | 0.78 | STAT3 (0.63) | STAT3ELANEALDH1A1GAA | |
| SCHEMBL20187544 | 0.78 | STAT3 (0.63) | STAT3ELANEALDH1A1GAA | |
| SCHEMBL10952444 | 0.76 | ELANE (0.60) | ELANECTSGALDH1A1TYR | |
| SCHEMBL20187614 | 0.74 | STAT3 (0.58) | STAT3ELANECTSGALDH1A1GAA | |
| SCHEMBL20189094 | 0.74 | STAT3 (0.58) | STAT3ELANECTSGALDH1A1GAA | |
| SCHEMBL20187597 | 0.73 | STAT3 (0.56) | STAT3ALDH1A1GAAERAP1 | |
| SCHEMBL20196459 | 0.73 | STAT3 (0.67) | STAT3ALDH1A1GAA | |
| SCHEMBL1450113 | 0.72 | STAT3 (1.00) | STAT3ELANECTSGALDH1A1 | |
| SCHEMBL20191214 | 0.71 | STAT3 (0.54) | STAT3ALDH1A1 | |
| SCHEMBL20187658 | 0.69 | STAT3 (0.58) | STAT3ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018096401-A1 | NEW NAPHTHO[2,3-B]FURAN DERIVATIVES | BAN HITOSHI (JP) | 2018-05-31 | — | — | WO | disclosed |