SCHEMBL201876

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2707360	0.89	HDAC6 (0.68)	PIK3CAPIK3CBPIK3CGPI4KBHDAC6
	SCHEMBL6629030	0.89	PIK3CA (0.61)	PIK3CAPIK3CBPIK3CGPI4KBNPC1
	SCHEMBL201231	0.87	PIK3CA (0.60)	PIK3CAPIK3CBPIK3CGPI4KBNPC1
	SCHEMBL3255507	0.87	PIK3CA (0.60)	PIK3CAPIK3CBPIK3CGPI4KBNPC1
	SCHEMBL17531862	0.83	NPC1 (0.65)	PIK3CAPIK3CBPIK3CGPI4KBNPC1
	SCHEMBL16809339	0.81	RAB9A (0.76)	PIK3CAPIK3CBPIK3CGPI4KBNPC1
	SCHEMBL1980717	0.81	PIK3CA (0.66)	PIK3CAPIK3CBPIK3CGPI4KBNPC1
	SCHEMBL202825	0.80	HDAC6 (0.62)	PIK3CAPIK3CBPIK3CGPI4KBNPC1
	SCHEMBL2756796	0.80	NPC1 (0.59)	PIK3CAPIK3CBPIK3CGPI4KBNPC1
	SCHEMBL21984788	0.79	PIK3CA (0.64)	PIK3CAPIK3CBPIK3CGPI4KBNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.