Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 5/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | TNFSF11 | O14788 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20189157 | 0.82 | STAT3 (0.66) | STAT3ALDH1A1CA9CA1CA2 | |
| SCHEMBL20187637 | 0.82 | STAT3 (0.66) | STAT3ALDH1A1CA9CA1CA2 | |
| SCHEMBL20187669 | 0.82 | STAT3 (0.57) | STAT3ALDH1A1LMNARECQLCA9 | |
| SCHEMBL20187648 | 0.82 | STAT3 (0.65) | STAT3ALDH1A1LMNARECQLHTT | |
| SCHEMBL20187658 | 0.80 | STAT3 (0.58) | STAT3ALDH1A1LMNARECQLCA9 | |
| Napabucasin SCHEMBL1883845 | 0.78 | STAT3 (1.00) | STAT3ALDH1A1LMNAHTTMAPT | |
| SCHEMBL14656628 | 0.76 | STAT3 (0.71) | STAT3ALDH1A1LMNARECQLHTT | |
| SCHEMBL14656586 | 0.76 | STAT3 (0.71) | STAT3ALDH1A1LMNARECQLHTT | |
| SCHEMBL20191216 | 0.75 | STAT3 (0.60) | STAT3ALDH1A1LMNARECQLMAPT | |
| SCHEMBL1882564 | 0.75 | STAT3 (0.69) | STAT3ALDH1A1LMNARECQLCA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018096401-A1 | NEW NAPHTHO[2,3-B]FURAN DERIVATIVES | BAN HITOSHI (JP) | 2018-05-31 | — | — | WO | claimed |
| WO-2018096401-A1 | NEW NAPHTHO[2,3-B]FURAN DERIVATIVES | BAN HITOSHI (JP) | 2018-05-31 | — | — | WO | disclosed |