Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 6/20 | 0.42 |
| ▸ | TTR | P02766 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20187576 | 0.82 | MEN1 (0.50) | MEN1KMT2AEGFRPIM1ELANE | |
| SCHEMBL5999780 | 0.75 | MAPT (0.52) | MEN1KMT2APOLBMAPTALDH1A1 | |
| SCHEMBL6000957 | 0.75 | MAPT (0.48) | MEN1KMT2APOLBCNR1MAPT | |
| SCHEMBL20189021 | 0.74 | KCNA3 (0.44) | MEN1KMT2AEGFRPIM1ELANE | |
| SCHEMBL20188852 | 0.73 | ELANE (0.47) | MEN1KMT2AEGFRPIM1ELANE | |
| SCHEMBL20187629 | 0.71 | MEN1 (0.48) | MEN1KMT2AEGFRPIM1ELANE | |
| SCHEMBL29339249 | 0.70 | EGFR (0.55) | MEN1KMT2AEGFRPIM1ELANE | |
| SCHEMBL6001534 | 0.70 | MAPK14 (0.48) | MEN1KMT2ATTRMAPTHPGD | |
| SCHEMBL6001053 | 0.69 | DYRK1A (0.47) | MEN1KMT2ATTRMAPTHPGD | |
| SCHEMBL20187695 | 0.69 | MAPT (0.47) | MEN1KMT2AEGFRPIM1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018096401-A1 | NEW NAPHTHO[2,3-B]FURAN DERIVATIVES | BAN HITOSHI (JP) | 2018-05-31 | — | — | WO | claimed |