Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TCF4 | P15884 | 1/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.41 |
| ▸ | TOP1 | P11387 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20189173 | 0.80 | MAPT (0.56) | MEN1KMT2AELANEALDH1A1MAPT | |
| SCHEMBL20187576 | 0.77 | MEN1 (0.50) | MEN1KMT2AEGFRPIM1ELANE | |
| SCHEMBL8947495 | 0.75 | EGFR (0.73) | MEN1KMT2AEGFRPIM1ELANE | |
| SCHEMBL10037460 | 0.74 | MAOA (0.58) | MEN1KMT2AELANEALDH1A1MAPT | |
| SCHEMBL3417492 | 0.74 | EGFR (0.76) | MEN1KMT2AEGFRPIM1ELANE | |
| SCHEMBL8996341 | 0.73 | EGFR (0.54) | MEN1KMT2AEGFRPIM1ELANE | |
| SCHEMBL612831 | 0.72 | MAPT (0.74) | MEN1KMT2AEGFRPIM1ELANE | |
| SCHEMBL23199074 | 0.72 | EGFR (0.59) | MEN1KMT2AEGFRPIM1ELANE | |
| SCHEMBL7463978 | 0.71 | MEN1 (0.53) | MEN1KMT2AEGFRPIM1ELANE | |
| SCHEMBL20187694 | 0.71 | MEN1 (0.43) | MEN1KMT2AEGFRPIM1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018096401-A1 | NEW NAPHTHO[2,3-B]FURAN DERIVATIVES | BAN HITOSHI (JP) | 2018-05-31 | — | — | WO | claimed |