Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 4/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.42 |
| ▸ | SLC37A4 | O43826 | 2/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.42 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.42 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | CTH | P32929 | 1/20 | 0.40 |
| ▸ | CTSG | P08311 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20187588 | 0.87 | L3MBTL1 (0.47) | ELANEALOX5SLC37A4MEN1KMT2A | |
| SCHEMBL20187576 | 0.82 | MEN1 (0.50) | ELANESLC37A4FGFR1SRCFGFR2 | |
| SCHEMBL20189021 | 0.78 | KCNA3 (0.44) | ELANESLC37A4FGFR1SRCFGFR2 | |
| SCHEMBL20187694 | 0.73 | MEN1 (0.43) | ELANEMEN1KMT2AEGFRPIM1 | |
| SCHEMBL20188827 | 0.72 | PSMB11 (0.47) | SLC37A4MEN1KMT2AMMP1MMP2 | |
| SCHEMBL16672533 | 0.71 | NPC1 (0.63) | ALOX5KMT2ATTR | |
| SCHEMBL28200963 | 0.71 | MEN1 (0.62) | ALOX5MEN1KMT2ATTRMMP1 | |
| SCHEMBL20187629 | 0.69 | MEN1 (0.48) | ELANEMEN1KMT2AEGFRPIM1 | |
| SCHEMBL612831 | 0.66 | MAPT (0.74) | ELANEMEN1KMT2AEGFRPIM1 | |
| SCHEMBL8947495 | 0.66 | EGFR (0.73) | ELANEMEN1KMT2AEGFRPIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018096401-A1 | NEW NAPHTHO[2,3-B]FURAN DERIVATIVES | BAN HITOSHI (JP) | 2018-05-31 | — | — | WO | claimed |
| WO-2018096401-A1 | NEW NAPHTHO[2,3-B]FURAN DERIVATIVES | BAN HITOSHI (JP) | 2018-05-31 | — | — | WO | disclosed |