SCHEMBL20187959

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20187769	0.79	APLNR (1.00)	APLNRHPGDTSHRHSD17B10ALDH1A1
	SCHEMBL20190468	0.77	APLNR (1.00)	APLNRHPGDTSHRHSD17B10ALDH1A1
	SCHEMBL17298109	0.77	APLNR (0.74)	APLNRMAPTHPGDTSHRHSD17B10
	SCHEMBL20207578	0.77	APLNR (0.75)	APLNRTSHR
	SCHEMBL20189127	0.76	APLNR (1.00)	APLNR
	Hydrochloric Acid SCHEMBL19095396	0.76	APLNR (0.73)	APLNRMAPTHPGDTSHRHSD17B10
	Hydrochloric Acid SCHEMBL31608490	0.76	APLNR (0.73)	APLNRMAPTHPGDTSHRHSD17B10
	SCHEMBL20189712	0.75	APLNR (1.00)	APLNRTSHRHSD17B10MAPK1
	SCHEMBL20189941	0.71	APLNR (1.00)	APLNRHPGDTSHRHSD17B10ALDH1A1
	SCHEMBL30506315	0.69	HSD17B2 (0.76)	MAPTTSHRALDH1A1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.