Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17844801 | 0.77 | HTT (0.52) | LMNAKDM4ECYP1A2 | |
| SCHEMBL22526055 | 0.76 | CYP4F2 (0.41) | CYP4F2CYP4A11KCNH2TMEM97SIGMAR1 | |
| SCHEMBL23845279 | 0.75 | CYP4F2 (0.37) | CYP4F2CYP4A11KCNH2TMEM97SIGMAR1 | |
| SCHEMBL20191206 | 0.75 | APP (0.50) | LMNAKDM4ETP53 | |
| SCHEMBL20189994 | 0.74 | ALDH1A1 (0.41) | CYP4F2CYP4A11KCNH2TMEM97SIGMAR1 | |
| SCHEMBL29307149 | 0.74 | CYP4F2 (0.36) | CYP4F2CYP4A11KCNH2TMEM97SIGMAR1 | |
| SCHEMBL22723271 | 0.74 | SMN1; SMN2 (0.38) | SMN1; SMN2 | |
| SCHEMBL22723270 | 0.74 | SMN1; SMN2 (0.38) | SMN1; SMN2 | |
| SCHEMBL28003037 | 0.73 | ATM (0.59) | KDM4ECYP1A2 | |
| SCHEMBL22525834 | 0.73 | FUT7 (0.38) | KCNH2TMEM97SIGMAR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098206-A1 | HYDANTOIN CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |