Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FUT7 | Q11130 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22526055 | 0.83 | CYP4F2 (0.41) | KCNH2TMEM97SIGMAR1 | |
| SCHEMBL23845279 | 0.82 | CYP4F2 (0.37) | KCNH2TMEM97SIGMAR1 | |
| SCHEMBL29307149 | 0.81 | CYP4F2 (0.36) | KCNH2TMEM97SIGMAR1 | |
| SCHEMBL20189994 | 0.79 | ALDH1A1 (0.41) | KCNH2TMEM97SIGMAR1ALDH1A1GAA | |
| SCHEMBL10776243 | 0.74 | STAT3 (0.55) | SIGMAR1MEN1CYP1A2POLBCYP3A4 | |
| SCHEMBL20188093 | 0.73 | CYP4F2 (0.39) | KCNH2TMEM97SIGMAR1CYP1A2 | |
| SCHEMBL24225596 | 0.73 | ALDH1A1 (0.44) | ALDH1A1GAAKDM1A | |
| SCHEMBL16047309 | 0.72 | STAT3 (0.49) | KCNH2TMEM97SIGMAR1ALDH1A1TSHR | |
| SCHEMBL10289878 | 0.72 | ALDH1A1 (0.48) | ALDH1A1GAANPSR1KDM1A | |
| SCHEMBL26206475 | 0.71 | S1PR2 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020206424-A1 | STAT DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2020-10-08 | — | — | WO | disclosed |